Children's Hospital Colorado
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Articles

Outcome of Antibody-Mediated Fetal Heart Disease with Standardized Anti-Inflammatory Transplacental Treatment

In this study, in utero fetal treatment with steroids for atrioventricular block, a manifestation of fibrosis due to inflamed fetal heart tissue in fetuses with neonatal lupus erythematosus, improved survival and decreased dilated cardiomyopathy.

Articles

Testing Levels of Anti-Ro/SSA Antibodies in Pregnant Patients to Identify Risk of Fetal Atrioventricular Block

Researchers defined anti-Ro/SSA antibody thresholds that can accurately identify pregnancies unlikely to develop fetal atrioventricular block, thereby reducing the need for costly and time-consuming ongoing fetal echo surveillance in pregnant patients.

Articles

Optimizing Pediatric Liver Transplant Outcomes with Living Donors

Researchers from the largest volume center for pediatric living-donor liver transplants found that offering living donations at a high-volume transplant center can reduce time on the waiting list and improve outcomes.

Articles

3D Intracardiac Echocardiography: Changing the Standard of Care for Cardiac Catheterizations

Children’s Hospital Colorado was the first pediatric hospital to use the recently FDA-approved 3D intracardiac echocardiography (ICE) catheter from Phillips. With superior, high-resolution imaging, 3D ICE allows cardiac interventionalists to better navigate complex cardiac procedures without any significant additional time, risk or access points.

Articles

Acetaminophen Toxicity in Premature Lungs

Acetaminophen is often used in neonatal intensive care units to treat newborns with patent ductus arteriosus. But given its impact on the liver, researchers at Children’s Hospital Colorado investigated how it affects premature lungs.

Articles

Therapeutic Approach to Treating Congenital Diaphragmatic Hernia

The Colorado Fetal Care Center at Children’s Hospital Colorado achieves some of the best survival rates for the most severe cases of congenital diaphragmatic hernia –– thanks to early therapeutic repair on extracorporeal membrane oxygenation.

Articles

The Cancer that Changes its Spots: How Acute Lymphoblastic Leukemia Changes to Acute Myeloid Leukemia

For years, doctors have faced a difficult challenge in treating a subtype of B-cell acute lymphoblastic leukemia, which is known to change to acute myeloid leukemia –– easily evading CAR T-cells and significantly limiting treatment options.

Articles

Predictors of Survival Following Liver Transplantation for Pediatric Hepatoblastoma and Hepatocellular Carcinoma: Experience from the Society of Pediatric Liver Transplantation

Researchers reviewed data from children who had liver transplant for two types of liver tumors: hepatoblastoma and hepatocellular carcinoma. Despite varying outcomes, the data support liver transplantation to treat advanced tumors.

Articles

The Role of Epigenetics in Adolescent Idiopathic Scoliosis

Adolescent idiopathic scoliosis is one of the most common forms of scoliosis. Although researchers haven’t identified the exact cause, researchers are working to better understand how epigenetic, or environmental, factors play a role in disease onset.

Articles

Evidence-Based Behavioral Strategies for Children’s Sleep in Smartphone Apps: Content Analysis

While there are dozens of sleep apps for children, few align with evidence-based behavioral strategies for improving pediatric sleep. Here’s a review of 83 smartphone apps for sleep.