Children's Hospital Colorado
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Articles

HEROS: An Early Remote SARS-CoV-2 Study of Households with Children

An early, 12-city remote study of SARS-CoV-2 infection within U.S. households with children. HEROS used sample self-collection for detection of viral RNA in nasal secretions to gauge infection rate and transmission in families.

Articles

Speeding Up Cardiac Disease Research with Big Data

Researchers at Children's Hospital Colorado's Pediatric Heart Institute are utilizing big data to speed up discovery. By adopting business world techniques, the researchers apply a data-driven, inductive approach, using blood tests to measure biomarkers and machine learning to sort the data, leading to the development of new research questions and speeding up the discovery process.

Articles

Transforming Pediatric Mental Health Care

The team at Children's Hospital Colorado is radically transforming pediatric mental health care to address the rising mental health crisis among kids. Their comprehensive approach includes implementing a trauma-informed care system, reducing inpatient care wait times, significantly expanding outpatient services and more.

Articles

More Extensive Lymph Node Sampling During Pediatric Renal Tumor Surgery Does Not Increase Postoperative Complications

Concerns about risk has led to low lymph node sampling rates during renal tumor surgeries despite value for treatment and disease staging. This study found it caused no rise in complications.

Articles

Single Center Case Series Highlights Successful Intra-Operative Continuous Renal Replacement Therapy for Pediatric Liver Transplant Recipients

Acute kidney injury is common in pediatric patients who need a liver transplant. Often used in adults, continuous renal replacement therapy can help stabilize pediatric patients during transplant.

Articles

Drug Combo Shows Therapeutic Promise for Group 3 MYC-Driven Medulloblastoma

Discover how our pediatric cancer researchers found new hope for treating deadly group 3 MYC-driven medulloblastoma with the drug combo tacedinaline and anti-CD47.

Articles

Advances in Precision Medicine for Rare Diseases

Children’s Hospital Colorado launched the Precision Medicine Institute to improve access to genomic and genetic testing and targeted novel therapeutics for patients, particularly children with rare diseases. Precision medicine utilizes genetics, environmental factors and large genomic data sets to provide quicker diagnoses and targeted treatments for patients.

Articles

A Home for Vascular Anomalies Care

Children's Hospital Colorado's Vascular Anomalies Center offers a groundbreaking multidisciplinary approach to diagnosing and treating vascular anomalies, effectively revolutionizing patient care. Spearheaded by experts, including Dr. Taizo Nakano, the center has developed a new classification system and consensus guidelines, and established an academic infrastructure for clinical trials.

Articles

Vincristine Exposure and Sex-Specific Impact on Lower Urinary Tract Function

A study of vincristine (VCR), commonly used in childhood cancer treatment, found sex-specific impacts to lower urinary tract function in mouse models, suggesting the risk of a potential side effect in childhood cancer survivors.

Articles

Toward Greater Nuance in Delayed Cord Clamping

Researchers explore delayed cord clamping (DCC) benefits for term and preterm infants, finding improved survival and reduced complications. DCC implementation varies, but evidence supports benefits for historically excluded populations.