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Articles

Single Center Case Series Highlights Successful Intra-Operative Continuous Renal Replacement Therapy for Pediatric Liver Transplant Recipients

Acute kidney injury is common in pediatric patients who need a liver transplant. Often used in adults, continuous renal replacement therapy can help stabilize pediatric patients during transplant.

Articles

Drug Combo Shows Therapeutic Promise for Group 3 MYC-Driven Medulloblastoma

Discover how our pediatric cancer researchers found new hope for treating deadly group 3 MYC-driven medulloblastoma with the drug combo tacedinaline and anti-CD47.

Articles

Advances in Precision Medicine for Rare Diseases

Children’s Hospital Colorado launched the Precision Medicine Institute to improve access to genomic and genetic testing and targeted novel therapeutics for patients, particularly children with rare diseases. Precision medicine utilizes genetics, environmental factors and large genomic data sets to provide quicker diagnoses and targeted treatments for patients.

Articles

A Home for Vascular Anomalies Care

Children's Hospital Colorado's Vascular Anomalies Center offers a groundbreaking multidisciplinary approach to diagnosing and treating vascular anomalies, effectively revolutionizing patient care. Spearheaded by experts, including Dr. Taizo Nakano, the center has developed a new classification system and consensus guidelines, and established an academic infrastructure for clinical trials.

Articles

Vincristine Exposure and Sex-Specific Impact on Lower Urinary Tract Function

A study of vincristine (VCR), commonly used in childhood cancer treatment, found sex-specific impacts to lower urinary tract function in mouse models, suggesting the risk of a potential side effect in childhood cancer survivors.

Articles

Toward Greater Nuance in Delayed Cord Clamping

Researchers explore delayed cord clamping (DCC) benefits for term and preterm infants, finding improved survival and reduced complications. DCC implementation varies, but evidence supports benefits for historically excluded populations.

Articles

Evaluating the Role for Regional Analgesia in Children With Spina Bifida

Examining opioid and non-opioid analgesics before, during and after urology surgery for spinal bifida patients revealed significant differences between the two groups, with much greater use of non-opioid adjuncts and decreased opioid use in the group who received regional catheters.

Articles

Venetoclax with Radiation Attenuates Diffuse Midline Glioma Growth

Pre-clinical study results demonstrate the potential use of venetoclax combined with radiation therapy for pediatric diffuse midline glioma and warrants a phase 1b clinical trial.

Articles

Airway Inflammation in Children with Primary Ciliary Dyskinesia

This study provides more knowledge into the role of lower airway inflammation in the development of primary ciliary dyskinesia lung disease.

Articles

The Benefits of Fetal MRI Scans for Placenta Complications

A new study explores the benefits of combining MRI scans with a quantitative risk scale to help confirm serious placenta conditions, which will help pregnant patients make more informed decisions and better equip care teams when creating treatment plans.